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At the same time, single-cell epigenomic studies suggest that microglia and astrocytes can enter long-lasting, reprogrammed states, retaining aspects of prior immune experience rather than returning to a naive baseline

Results tend to be gradual rather than rapid

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This experience allowed him to gain a deeper understanding of the issue

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As a reference, recombinant IGF-1 injections have a half-life of under 6 hours when given subcutaneously as a treatment of growth failure and slower development of children due to poor IGF-1 levels