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In advanced cancer, the high expression of GPX3 clears excess ROS in the extracellular environment, maintaining the redox homeostasis in the TME, protecting tumor cells and enhancing drug resistance (88)
Nat Rev Neurosci 5 : 952962
82 HanH.YinJ.WangB.HuangX.YaoJ.ZhengJ.et al
Long-term efficacy and safety of levonorgestrel-releasing intrauterine system as a maintenance treatment for endometriosis
therefore more metabolites must be explored for direct influence on BBB physiology
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