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Most participants on 8 mg and 12 mg reached major weight loss milestones, including at least 1015% weight loss

A review of their potential efficacy and suitability

Finally, there are known gender differences in body composition [47]

We proposed that the insulinotropic effect of this GLP-1R agonist (GLP-1RA) would synergize with the insulin-sensitizing effect of tesaglitazar to optimize glucose handling, while the body weight lowering effect of the GLP-1RA would buffer against any potential obesogenic activity of PPAR agonism