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Understanding stem cell activation raises an important question about the underlying mechanisms that make this process possible

However, the direct impacts of stress-induced oxidation of nuclei have significant implications for current concepts of redox sensing and regulation, as well as associated signal transduction pathways (Sevilla et al

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doi: 10.1111/bjd.14477

And they connect the receptor to the cell internalization machinery, specifically clathrin-coated pits that pull the receptor off the cell surface and into intracellular compartments called endosomes