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Although GLP-1 drugs are generally considered safe to use, its recommended to avoid them if you have or had: Personal or family history of thyroid cancer Family history of multiple endocrine neoplasia 2 (MEN-2) Pancreatitis Used other anti-obesity medications These medications can aggravate the above conditions, which may lead to serious health complications

GLP-1 receptor agonists have demonstrated anti-inflammatory effects in both animal and human studies

Holmes et al., 1999

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Despite limitations of comparisons across trials, some overall themes emerge