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The 2025 Frontiers in Aging clinical review (Frontiers in Aging 2025) summarises the documented short-term adverse effects in adult populations: peripheral oedema and fluid retention are common at initiation, carpal tunnel syndrome occurs in a meaningful proportion of users, hyperglycaemia and insulin resistance can emerge because GH is physiologically counter-regulatory to insulin, and gynaecomastia has been reported, particularly at higher doses

Dissociation of body mass index, excess weight loss and body fat percentage trajectories after 3 years of gastric bypass: relationship with metabolic outcomes

Please refrain from adjusting your medication or schedule without first consulting your healthcare provider

the most frequently reported reactions were nausea, vomiting, and diarrhea

Your provider can help determine if your dosage needs to be adjusted or if you require additional support to manage side effects

In health the best medicine is always preventive