The three most common active ingredients used in GLP-1s are semaglutide, liraglutide, and tirzepatide
It's also important to understand that microneedling results are not permanent natural aging and collagen degradation continue over time, so maintenance treatments may be recommended

Kardie Tobb, DO, MS, FASPC, FACC, a boardcertified preventive cardiologist and the medical director for the Cone Health HeartCare Women's Heart Health and Cardio-Obstetrics Clinic, explains some of the most common reasons why GLP-1s may not deliver the results you're hoping for, including: You need a higher dose and have not yet reached a therapeutic dose as determined by your doctor High intake of liquid calories , including alcohol and ultra-processed foods Not getting enough protein , which can leave you persistently hungry and makes it harder to feel full Advanced diabetes or insulin resistance Taking other medications such as sulfonylureas, which lower blood sugar but can lead to weight gain Not adhering to your dosing schedule , such as inconsistent weekly injections or missed doses Differences in gut hormones or genetics And just because your GLP-1 isn't working immediately doesn't mean it won't work for you
Do I need a doctor's letter to fly with GLP-1 injection pens
Semaglutide doses cap at 2.4 mg weekly, and exceeding this carries increased side effect risk without guaranteed additional weight loss
Lipid Peroxidation