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While this requirement may narrow some claims, it streamlines the litigation as the court prepares to address broader issues like federal preemption and general causation

Some patients also report increased energy or mood changes during semaglutide treatment, which can create a sense of alertness that interferes with sleep onset

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PIONEER 1 to 5, 8, and 9 were adequately powered to detect a change from baseline in A1C as the primary outcome, as well as change from baseline in body weight as the key secondary outcome (except PIONEER 9)

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