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However, rare and serious complications can occur, such as acute pancreatitis (indicated by severe, persistent stomach pain that radiates to your back)

Ganju and colleagues concluded, These results provide the first large-scale evidence supporting GLP-1RAs as a safe and potentially beneficial adjunct in Crohns disease management. They went on to note that prospective studies and guideline development are urgently needed to define their role in integrated IBD and metabolic care.

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8.1 Challenges in the optimization of multi-receptor agonists Although multi-receptor agonists such as tirzepatide exhibit enhanced effectiveness, their development poses distinct obstacles that need careful attention