Stopping GLP-1 therapy often leads to weight regain unless long-term lifestyle changes are maintained
Semaglutide and tirzepatide allow for albumin binding and resistance to DPP4 degradation, creating a significantly longer half-life (5 days for tirzepatide and 7 days for semaglutide) and thus a greater effect on receptors and downstream pathways in the central nervous, cardiovascular, digestive, and musculoskeletal systems as described below [37, 38]
No increase in thyroid cancer has been observed in clinical trials, though very rare cases have been reported post-marketing
Patients can undergo a tummy tuck or body lift with their surgeon and then return to the same practice for RF microneedling, laser treatments, or injectable services all coordinated under one roof
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