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Un farmaco non nasce gi pronto per la clinica, passa per studi preclinici, poi per tre fasi sperimentali sulluomo: fase 1 (studi su esseri umani sani)

2020;43:S98110

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Ralston J, Brinsden H, Buse K, et al

Reliable quantification of individual NAD metabolites and glutathione can be achieved through liquid-chromatography mass-spectrometry (LC-MS) 22 , cyclic enzymatic assays and high-performance liquid chromatography (HPLC) 2326 , but these have not been applicable for the scalable analysis of the whole redox set, especially from a single extract