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Tirzepatide was approved largely based on data from the SURPASS series of clinical trials

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These fatty acids have been associated with an increased ratio of Bacteroidetes to Firmicutes and a greater abundance of beneficial microbial populations, including lactic acid bacteria, Bifidobacterium , and Akkermansia muciniphila (2, 91)

He also explores how GLP-1based therapies affect different fat depots throughout the body, identifies who may be most vulnerable to muscle loss, and outlines practical strategies for preserving muscle and bone health while using these medications

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