Summary Takeaway Messages Despite the ability of GLP-1s to produce significant weight reduction and related health benefits, challenges such as GI side effects, risk of nutrient inadequacies, loss of muscle and bone mass, high costs, frequent discontinuation, and weight regain limit the use of these drugs for long-term success in individuals and populations
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Semaglutide 2.4mg (marketed as Wegovy) represented the previous benchmark for injectable weight loss medications
While both groups improved muscle mass index by 2%3%, only the supplementation group showed a significant improvement in memory function (+0.3 points on cognitive testing), suggesting an additive benefit of soy peptides on cognitive domains alongside exercise ( P 80 yr) men: evidence for limited skeletal muscle plasticity
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Liu R, Cheng J, Wu H