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Olaparib, for instance, is an FDA-approved inhibitor of the enzyme poly ADP ribose polymerase (PARP) which can efficiently kill BRCA mutant tumor cells, a successful synthetic lethality based targeting strategy used in breast cancers and ovarian cancers (165)
(2006): Prolonged stimulation of growth hormone and insulin-like growth factor I secretion by CJC-1295 in healthy adults (J Clin Endocrinol Metab
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A mechanism for epithelialmesenchymal transition and anoikis resistance in breast cancer triggered by zinc channel ZIP6 and STAT3 (signal transducer and activator of transcription 3)
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