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J Nutr Sci Vitaminol

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The SELECT trial specifically demonstrated that semaglutide reduces major adverse cardiovascular events by 20% in patients with established cardiovascular disease, regardless of diabetes status

The article describes Retatrutide as a single peptide with agonist activity at GIP, GLP-1, and glucagon receptors and notes that the Phase 2 data informed later development planning

Additionally, the proportion of participants from ethnically diverse backgrounds was relatively small, as most of the RCTs included in this SRM were conducted in Europe and America

Roux-en-Y gastric bypass versus medical treatment for type 2 diabetes mellitus in obese patients: a systematic review and meta-analysis of randomized controlled trials