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The medication should be discontinued when pregnancy is recognized or before planned conception

Some people may experience even greater weight loss, with up to 25% of their body weight lost in longer studies, depending on the dosage and how well they follow their treatment plan

Tolerability Comparison# GI side effects are the primary tolerability concern for all GLP-1 drugs, regardless of route: Oral formulations do not appear to have inherently better or worse GI tolerability than injectables

38(3): 32431 Wiley V, Carpenter K, Wilcken B

Mitochondrial dysfunction in heart failure and its therapeutic implications

If the peptide is administered once in a way that creates a short signaling event, that protocol is functionally different from the same total amount divided across separate administrations