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doi:10.1038/ajg.2012.255 Kale-Pradhan PB, Wilhelm SM
We thank the Biological Services Unit at QUB for supporting the animal studies undertaken
When GLP-1 receptors (GLP-1Rs) on intraepithelial lymphocytes (IELs) are activated, there is a decrease in pro-inflammatory cytokine levels, a reduction in the expression of interferon-stimulated genes (ISGs), and a lower rate of apoptosis in epithelial cells [94,95]
Lim W, et al
The collected data were synthesized to provide an in-depth evaluation of luteolins mechanistic roles in treating PF, such as the multi-targeted mechanism of action in cell lines and preclinical models, advances in formulation strategies, and the need to link preclinical discoveries to clinical applications (refer to Fig