This was the case in our pre-registered primary analysis (where we report a significant group effect across groups of participants with type-2 diabetes, on and off semaglutide, and BMI-matched and -unmatched healthy controls, which numerically show decreasing acceptance bias), and in our exploratory dimensional finding that increasing risk of diabetes is associated with lower acceptance bias across study groups
Studies have shown that these medications can reduce the risk of heart attacks, strokes, kidney disease, obstructive sleep apnea and now possibly cancer
Inform us immediately if you are experiencing any pain, discomfort, heart palpitations, headaches, nausea, cramps, dizziness or if it becomes difficult for you to breathe
Indeed, while environmental and lifestyle factors alongside hormonal influences contribute to its pathogenesis, the strong familial disease clustering suggests also a significant genetic susceptibility
A joint advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and the Obesity Society explicitly states that restrictive eating disorder is a general contraindication to GLP-1 use and that individuals with a history of eating disorders should be referred to an eating disorders specialist before these medications are prescribed ( Mozaffarian et al., Am J Clinical Nutrition, 2025 )
2.5 mg is typically a maintenance dose in compounded formulations for semaglutide weight loss
