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For example, long-acting sustained-release formulations can be obtained through side chain modification, with a half-life that can be extended to 12 hours, meeting the clinical need for long-term maintenance of efficacy

however, in PD, the neurons producing dopamine slowly die out, causing an excess of acetylcholine to overstimulate the basal ganglia (Wang Q

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Proximal lymphangitis and lymphadenopathy may be observed

Over five years, NAION developed in 0.087% of the GLP-1 group versus 0.065% of the control group

This increases the risk of a heart attack, when blood flow to the heart muscle is compromised