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Quanto alle soglie di risposta, alla dose massima il 54,5% dei pazienti ha perso almeno il 10% del peso, il 36,0% almeno il 15% e il 18,4% almeno il 20%, contro il 12,9%, il 5,9% e il 2,8% del placebo (Wharton et al., 2025)

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Retatrutide, like other incretin-based agents, produces weight loss that includes a proportion of lean body mass alongside fat tissue, as observed with GLP-1 receptor agonist class data

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