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Anorexigenic and anti-inflammatory signaling pathways of semaglutide via the microbiota-gut--brain axis in obese mice

Donders GG, Vereecken A, Bosmans E, Dekeersmaecker A, Salembier G, Spitz B

This is an FDA-approved semaglutide injection specifically designed for weight management

Dissolution testing with an acid-sensitive model API confirmed complete compliance with the USP criteria for delayed-release dosage forms: no capsule opening occurred during 2 h in 0.1 N HCl, followed by rapid and complete opening within minutes after transfer to pH 6.8 phosphate buffer

Dizziness and headaches also have been reported