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The early weeks and the period after each dose increase are when any heart rate effect is most likely to present itself

What are the side effects of GLP-1 agonists

"Exosome-mediated neuroprotection in stroke: Mechanisms and clinical implications." Journal of Neuroinflammation , 21(1), 78-94

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Following a single oral 100 mg dose to healthy volunteers, mean plasma AUC of sitagliptin was 8.52 M-hr, C max was 950 nM, and apparent terminal half-life (t 1/2 ) was 12.4 hours