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The efficacy and safety of the new pharmacotherapies after bariatric surgery require further investigation, however the benefits of GLP-1 RA after bariatric surgery on WL and glycaemia have been shown in clinical trials [103, 104]

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Three major classes of sensors translate these signatures into downstream responses: calmodulins (CaM), Ca 2 -dependent protein kinases (CDPKs), and calcineurin B-like proteins (CBLs) (Tokas et al

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