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Calabresi, Johns Hopkins University ( Photo Provided ) Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system, causing problems with nerve cells and leading to symptoms, such as numbness, tingling, motor deficit, depression, fatigue, visual loss, and cognitive dysfunction

The chronic activation of the type I IFN pathway is a hallmark of SLE and contributes to the dysregulation of immune responses in this disease [132]

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