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GHK-CU is a copper(II)-complexed tripeptide (molecular weight: ~401 g/mol) consisting of glycine-histidine-lysine chelated to copper ions, naturally present in human plasma

Supports skin that looks smoother and more refined with consistent nightly use

The computed energy barrier for Cu(II)-catalyzed methionine oxidation is 14.3 kcal/mol significantly lower than for Zn (19.6 kcal/mol) or Fe (16.9 kcal/mol), making copper the most efficient catalyst among common metal ions

Palmitoyl Pentapeptide-4 (Matrixyl): A topical peptide that stimulates collagen synthesis and visibly reduces wrinkles

Gadovist, Bayer Schering, Berlin, Germany)

10.3233/JAD-2012-120268 199