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Abstract Glucagon-like Peptide-1 (GLP-1) receptor agonists (GLP-1RAs) emerged as a primary treatment for type-2 diabetes mellitus (T2DM), however, their multifaceted effects on various target organs beyond glycemic control opened a new era of treatment

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GLP-1 therapy is used to treat type 2 diabetes, sleep apnea, and obesity, and supports weight loss by suppressing appetite and reducing "food noise." Many patients also notice improved cholesterol and blood pressure measurements and reduced inflammation