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The increase in Lac-Phe production induced by metformin is directly related to the inhibition of complex I of the oxidative phosphorylation machinery

Finally, Drosophila do not have an adaptive immune system, which complicates both the study of tissue restitution after injury and the underlying crosstalk with intestinal microbes

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Optimizing ophthalmic delivery of a poorly water soluble drug from an aqueous in situ gelling system

For gut and nerve conditions, systemic SubQ or oral routes are appropriate