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There is a similar beneficial effect in the rats with the Pringle maneuver, ischemia, reperfusion, and suprahepatic inferior caval vein occlusion (BuddChiari syndrome) (Vukojevic et al., 2018

Many people seem to experience symptoms like those you mention - where it has been mentioned in posts my memory is that the individuals concerned report the sleepiness as something that continues as they move into maintenance shots

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