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while reductions in HbA 1C levels were observed across all intervals, participants having lived with diabetes for less than a year showed the highest estimated HbA 1C reduction, 1.7%-points (95% CI 1.86 to 1.57) or 18.8 mmol/mol (95% CI 20.40 to 17.17) (Fig

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Metformin contains no sulfonamide compounds and is generally well-tolerated, though gastrointestinal side effects can occur initially