We constructed standardized experimental models encompassing murine full-thickness burn injuries [13], rat dermal incisional wounds [13], and rodent skeletal muscle contusion models (Figure S1)
Besides counteraction of bleeding aspirin-gastric ulcers (14), BPC 157 also counteracts other NSAIDs-toxicity, using the same dose range (8-14), namely, gastric and small intestine ulcers (i.e., induced by indomethacin, diclofenac, ibuprofen, celecoxib (8-14)), hepatotoxicity (paracetamol, diclofenac, ibuprofen, celecoxib) (8-14) and encephalopathy (paracetamol, diclofenac, ibuprofen, celecoxib) (8-14)
The total milligrams in the vial determine how many weeks of doses you can draw before needing a new vial, and this calculation changes depending on where you are in your dose escalation schedule
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