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Dehydration, changes in blood glucose levels, and electrolyte shifts during the first 12 weeks of therapy may contribute to head pain in susceptible individuals

Some people need a different drug or a higher dose

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The abdomen, at least two inches from the navel, offers the most consistent absorption

Effect of Additional Oral Semaglutide vs Sitagliptin on Glycated Hemoglobin in Adults With Type 2 Diabetes Uncontrolled With Metformin Alone or With Sulfonylurea: The PIONEER 3 Randomized Clinical Trial