The real-world results we see in clinic come from combining a GLP-1 medication with structured nutrition advice, regular weighing-in, and a clinician available to manage side effects
This happens because the dapagliflozin in the medication works by helping your kidneys remove excess glucose from your body through urine
GLP-1 receptors in the gut mediate gastric emptying, intestinal motility, and nausea signaling
(NEJM 2023) reported 24.2% body-weight reduction at 48 weeks on retatrutide 12 mg [5]
Others prefer evening injection, hoping to sleep through the initial adjustment window
Reduced Inflammation Research suggests GLP-1 receptor agonists may lower signs of chronic, low-grade inflammation, including markers like C-reactive protein, and may also improve oxidative stress in the body