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It is suitable for any skin type and results in a noticeably softer, smoother, more refined skin texture

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Dose Adjustments: Renal Insufficiency: Patients with severe kidney disease require very close monitoring

This includes: Structured dietary programmes with regular dietetic input Supervised exercise regimens tailored to individual capabilities Behavioural therapy addressing eating patterns and psychological factors Regular monitoring of weight, metabolic parameters, and medication adherence For patients with severe obesity (BMI 40 kg/m or 35 kg/m with comorbidities) who have not achieved adequate weight loss with optimal medical management, bariatric surgery offers the most effective long-term solution

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