parkeri from ROS, we hypothesized that if the antimicrobial effects of BSO were mediated through ROS, bacterial abundance would be increased upon inhibiting nitric oxide (NO) production
But it can only bind to those receptors if its molecular shape remains intact
Corticosteroids promote: Insulin resistance : reducing the body's ability to utilise glucose effectively Increased hepatic gluconeogenesis : stimulating the liver to produce more glucose Lipogenesis : promoting fat synthesis and storage Redistribution of body fat : encouraging central adiposity Hyperglycaemia : elevating blood sugar levels, which can progress to steroid-induced diabetes These metabolic disturbances directly counteract the therapeutic goals for managing fatty liver disease
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