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This process is inherently "leaky," naturally producing small amounts of ROS

Collectively, regardless of disease status, this cohort of children from a konzo-affected region show signs of protein malnourishment, harbor measures of mitochondrial distress, and deficiencies in a key sulfur-containing amino acid (Cystine)

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doi: 10.1038/s41398-022-02297-y 112 KatzAAWainwrightSKellyMPAlbertPByrneR

Antioxidant Activity GHK-Cu strengthens endogenous antioxidant defenses by increasing the expression of superoxide dismutase (SOD), glutathione peroxidase, and ferritin

10.1074/jbc.M805711200 40 LeiL.WangW.XiaC.LiuF