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These cells, also known as senescent or zombie cells, seem to be stuck between life and death

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In humans, given an oral capsule of 200 mol, the peak plasma was reported to have a Cmax of 0.7 0.2 M at 3 h, with a half-life of 1.9 0.4 h for elimination [115]

Only the concentration and the corresponding syringe draw change

For this reason, surgically sewing together a tear can be like sewing damaged tissue paper to damaged tissue paper, which is why we see very high re-tear rates after surgery (7)