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GIP medications are still in the experimental stages, with ongoing research exploring their potential benefits in weight management and metabolic health

GLP-1RAs have reliable hypoglycaemic and weight-loss effects that can intervene in obesitythe basis of type 2 diabetes pathologyand multifaceted effects on other cardiometabolic parameters, such as blood pressure and circulating lipids [21]

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reported that 12 weeks of resistance training at different intensities had no significant effect on BMD in elderly women with osteoporotic obesity

Hunger increases slightly

Clinical trial data from the SUSTAIN and STEP programs indicate that nausea, the most frequently reported side effect, generally improves within 46 weeks for most patients as tolerance develops