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Patients with active or recent malignancy warrant particularly careful evaluation given the theoretical concerns that apply to any compound with effects on cellular metabolism

Individual genetic predispositions, baseline metabolic state, and comorbidities influence whether patients achieve weight loss and metabolic benefits at standard starting doses

PlexusDx specializes in personalized medication selection

This evaluation forms the basis for physician-guided decision-making regarding semaglutide eligibility and dosing strategy

While its primary action involves p53 release, the modulation of FOXO4-related pathways intersects with cellular stress-response systems

J., Melioli, G., Canonica, G