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Real-World Implications for Semaglutide Taken together, GLP-1RA-nave T2D patients in the Netherlands treated with oral semaglutide achieved significant reductions in body weight and HbA1c

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The durability of results confirms that semaglutide appetite suppression is sustained over extended treatment periods, which matters for people evaluating how long to stay on semaglutide

Pharmacol Res (2018) 130:13242

2025 result report: Calibrate delivers longitudinal real-world outcomes

This dual action may support stronger appetite control and improved glucose management