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The early discovery in 2002 of the MC 1 selective compound BMS-470539 (200) together with the use of mice deficient in Mc1r may have helped to point to a role for MC 1 in fibroblast functions, as discussed earlier in section 4.3

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Metabolism of GLP-1 and the therapeutic actions of long-lasting agonists GLP-1 has an extremely short half-life once released in the plasma, ranging from 211 minutes(Deacon et al., 1995

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MM: Conceptualization, Methodology, Validation, Writing original draft, Writing review & editing