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Focus your application on the areas with inactive follicles, rather than completely bald regions where follicles have been dead for years

PubMed, Fuhrman, Bianca

'The usual ones' isn't an answer

In the chronic phase, persistent activation signals from factors including TGF- and PDGF lead to sustained fibroblast activity and continuous ECM production (136138)

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These models are validated by their ability to reproduce a diversity of new experimental results, and can be used as platforms for in-silico experimentation to determine the underlying mechanisms that give rise to the behavior seen in the clinic and experiments