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The key markers here are: Serum creatinine and estimated glomerular filtration rate (eGFR) the standard measures of kidney filtration capacity Blood urea nitrogen (BUN) a secondary marker that rises when the kidneys struggle Urine albumin-to-creatinine ratio (uACR) especially relevant in patients with diabetes or hypertension, where early kidney damage often manifests as protein leaking into urine before eGFR declines From a dosing standpoint, most GLP-1 prescribing information does not require dose adjustment until eGFR falls significantly, but patients with an eGFR below 60 mL/min/1.73m warrant more frequent monitoring and clinical discussion about hydration strategy.[4] Ask: "Based on my kidney function, are there any specific precautions I should follow, and when do we recheck these markers?" Question 4: Do I Need a Thyroid Panel, Given the Warnings on the Label

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[12] [1] Severe gastrointestinal symptoms that limit your ability to maintain adequate nutrition or hydration

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PMID:15591001 Rebouche CJ