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In the main trial approximately 47% of participants discontinued treatment due to adverse events, depending on the dose, with higher doses linked to increased discontinuation

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People with Vitamin B12 deficiencies due to dietary or medical reasons

Euglycemic DKA (ketoacidosis without markedly elevated blood glucose) can occur and requires immediate medical attention

Lilly also expanded beyond obesity drugs this week through vaccine deals worth up to $3.8 billion, while late-stage data for Retatrutide showed up to 28% weight loss

Clinical pharmacokinetic studies measure actual nutrient absorption by tracking plasma concentrations over time [24] [25]