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No, semaglutide is specifically designed as a once-weekly injection

Both forms of semaglutide are considered suitable for long-term use, but like any drug, each must be observed by a patients healthcare professional on an ongoing basis for signs of adverse effects over time

Risks of Staying in a Calorie Deficit for Too Long Prolonged calorie restriction risks nutritional deficiencies, bone loss, metabolic adaptation, weight cycling, and an association with disordered eating behaviours including binge eating disorder and anorexia nervosa

As such, there has been a wave of investment in the GLP-1 space

That recommendation applies directly to the first 8-12 weeks of semaglutide therapy

PMCID: PMC10748240