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Professor John Deanfield (UCL Institute of Cardiovascular Science), the studys lead author, said: Abdominal fat is more dangerous for our cardiovascular health than overall weight and therefore it is not surprising to see a link between reduction in waist size and cardiovascular benefit

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Nature 418(6898):650654

In 2019, a proof of concept, phase IIa open label study in Germany aimed to evaluate the safety and efficacy of melanotan I implants in patients with XP [12]

Though retatrutide is still being evaluated in Phase III trials, its almost certain that it will receive regulatory approval in the U.S