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In animal models, findings suggest stronger responses in obese specimens compared to lean ones

The vegans averaged 0.76 grams of protein per kilogram of body weight per day (roughly 10% of daily calories from protein), while the Calorie Restriction members averaged 1.73 grams (roughly 24% of calories from protein)

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For example, a double-blind trial for semaglutide found that 86.4% of participants lost over 5% of their body weight in 68 weeks, while 13.6% did not