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(2023, The Lancet) Type 2 Diabetes Trial Study Design: Randomized, double-blind, placebo- and active-controlled Phase 2 trial in adults with type 2 diabetes

Etiology Gamma-glutamylcysteine synthetase catalyzes the first and rate-limiting step in the synthesis of glutathione (GSH) (Figure 1) [9]

This prolongs the sensation of fullness after meals, helping patients feel satisfied with smaller portions and reducing overall food intake

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The FDA also holds concerns regarding risks of incorrect dosage measurements, plus problematic side effects linked to unapproved GLP-1 drugs used for weight loss