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Niculescu A-G, Grumezescu AM

Current Management Blood transfusions - Thalassemia Major and some Thalassemia Intermedia patients require lifelong treatment in the form of regular blood transfusions to treat the severe anemia, promote growth and normal development

By far, the most common cause in this category is type 1 hemochromatosis related to mutations of the HFE gene, typically homozygous C282Y/C282Y or compound heterozygous C282Y/H63D

However, the populations most affected by diabetes and who could therefore benefit greatly from new treatments being studied are often the same groups left out of diabetes trials

Combining with AREDS2 supplements potentially additive benefits

10.1105/tpc.112.101964 Plant Cell 50 GigolashviliT.YatusevichR.RollwitzI.HumphryM.GershenzonJ.FlueggeU.-I