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In the SyM-BBB system, trapezoidal structures were used to model blood and brain compartments connected with 3-m microgaps (Prabhakarpandian et al., 2013)

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It is strongly believed that there are sites on the hypothalamus and pituitary glands that serve as points of action

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Relative to the control group, transcranial administration of a P2RX7 antagonist markedly reduced the number of neutrophils at the injury site

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A subsequent study describing the double incretin knock-out (DIRKO) mice showed that male Glp-1r / mice are only mildly glucose intolerant while females exhibited normal glucose tolerance after being backcrossed for five generations onto the C57BL/6 strain [5]

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