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These findings suggest that administering hepsin can effectively regulate GJ expression in wild-type mice, highlighting its potential as a therapeutic target to protect against APAP-induced hepatotoxicity, potentially in human patients

Figure 4 Statements Author contributions IC, BOB and SD conceived and planned the review

A member of S-transferase superfamily, GSTM1 has been reported to be associated with anti-RO antibodies suggesting that the dysfunction of this gene may contribute to the anti-Ro autoantibody response or to photosensitivity [66,67]